Comparison and Statistical Validation of Cerebral Flow Results Obtained Using Phase Contrast MRA and Computational Flow Dynamics in an In Vitro Cerebral Aneurysm Model
Dr. Frank Tong will lead a study to make a statistically valid comparison between flow model results obtained from in vitro MRA techniques and those obtained using computational fluid dynamics. Agreement between the two methods would validate their accuracy, while disagreement would raise interesting questions with regard to how to best apply and develop these methods for patient care.
This will be the first study of its kind to directly compare thesetechniques in a rigorous and statistically valid manner. Point by point agreement of the results would provide a valuable link between the in vitro and CFD research, while poor correlation will be the essential first step toward improving testing and optimization of both methods; while cautioning against blanket acceptance in clinical practice. The resulting improved understanding of optimal aneurysm modeling will ultimately prove valuable insight into accurately measuring and testing potential treatment and prevention strategies.
Carotid Artery Angioplasty and Stent Placement (CREST)
National study to evaluate the effectiveness of angioplasty and stenting of the carotid artery compared to the traditional surgical treatment.
Basic Science Laboratory Research
Basic research focuses on improvement of current devices used in intracranial aneurysm therapy in addition to examination of factors potentially causing aneurysm formation.