Developing MRI Based Methodology for Molecular and Cellular Imaging with Novel MRI Contrast Agents
Lead by: Hui Mao, PhD
The research in our group is supported by various funding agencies and organizations and is in collaborations with investigators from various departments.
Research projects in the area of neuroimaging include:
- Vascular Comorbidities and DTI Measured White Matter Damage in AD (NIH) that applies diffusion tensor imaging (DTI) to examine white matter damage and corresponding neuropsychological deficits in patients with Alzheimer's disease and mild cognitive impairment.
- Diagnosis of Diffuse Brain Injuries with Diffusion Tensor Imaging (DTI) and Functional Magnetic Resonance Imaging (GE Healthcare) is to develop a clinically feasible and comprehensive approach that will integrate fMRI and behavioral exam results with quantitative structural DTI exams in patients who have sustained moderate to severe traumatic brain injuries.
- Progressive Changes in Brain Activation in Paraplegia (NIH) which uses fMRI to investigate the brain activation, functional reorganization and plasticity of patients with complete spinal cord injury.
- Childhood Brain Tumor Survivors: Predictors of Adult Functional Outcomes (American Cancer Society) is to investigate the while matter development and executive functions of childhood brain tumor survivor to extract the predictive factors of the outcomes from the effect of the pediatric tumor and related treatment.
More details on related research projects on developing neuroimaging methods for studying neurodegenerative diseases and brain injuries:
http://whsc.emory.edu/press_releases2.cfm?announcement_id_seq=11303
Research projects in the area of molecular imaging and cancer nanotechnology include:
- Multifunctional Nanoparticles for Cancer Imaging is a part of the Program Project (NIH) of Emory-Georgia Tech Nanotechnology Center for Personalized and Predictive Oncology (CCNE) focusing on developing nanomaterial based imaging probes using QDs or magnetic iron oxide nanocrystals for cancer imaging. It is also supported by the grant from EmTech Bio, Inc.
- uPAR Targeted Magnetic Nanoparticles for Molecular MRI of Breast Cancer (NIH) is the project supported by the program project establishing Emory Translational Molecular Imaging Center (NIH P20).
More details on related research projects on developing nanomaterial based molecular imaging probe:
http://www.gatech.edu/news-room/release.php?id=667
http://nano.cancer.gov/programs/emory/projects.asp?projectId=0