
- Director: John Votaw, PhD
The mission of the Physics and Computing group is: extracting physiologic information from radiologic images, evaluating new radiotracers, improve the quantitative accuracy of PET imaging, and quality control of the PET scanners. There is a very close working relationship between this group and the radiopharmaceutical development lab. That lab provides all of the radiotracers and this lab provides all of the image analysis. Originally, our research was kinetic modeling of dynamic PET images. This included measuring the density of different proteins in the brain (DAT, SERT, NET, D2), amino acid transport into tumor tissue, and local cerebral glucose metabolism and blood flow under different sets of conditions. More recently, the kinetic modeling techniques have been used to determine renal blood flow and glomerular flitration rate from approximately dynamic sets of MRI data.
2 microPET scanners
HRRT scanner (high resolution PET brain imager)
3 whole body PET/CT scanners
2 multi node computer clusters
Kinetic Modeling of Gd Transport through Kidneys
Improved Attenuation Correction in Myocardial PET/CT Imaging
Application of Diffusion Tensor MRI to Study Neurologic Disease
Motion Correction in Neuro PET Imaging
Nonparametric Estimation of Fluid Velocity from Phase-Contrast MRI
Amino Acid Transport into Tumors as a Function of Tumor Grade
Comparision of Beta Amyloid Deposits in the Brains of Patients with Late Life Depression and Alzheimer’s Disease
Quantitative Myocardial Blood Flow Measurements
SERT Modeling in Depression
Therapeutic Drug Occupancy Studies.
John Votaw, PhD
Jon Nye, PHD
John Carew, PhD
Jacob David - Lab Manager
Nivedata Raghunath, MS
Dana Tudorascu
Mary David
E-mail: mary.david@emoryhealthcare.org