Research - Labs
Physics & Computing
Welcome
Director: John Votaw, PhD

The mission of the Physics and Computing group is: extracting physiologic information from radiologic images, evaluating new radiotracers, improve the quantitative accuracy of PET imaging, and quality control of the PET scanners.  There is a very close working relationship between this group and the radiopharmaceutical development lab.  That lab provides all of the radiotracers and this lab provides all of the image analysis.  Originally, our research was kinetic modeling of dynamic PET images.  This included measuring the density of different proteins in the brain (DAT, SERT, NET, D2), amino acid transport into tumor tissue, and local cerebral glucose metabolism and blood flow under different sets of conditions.  More recently, the kinetic modeling techniques have been used to determine renal blood flow and glomerular flitration rate from approximately dynamic sets of MRI data.

 

 

 

 

Resources

2 microPET scanners
HRRT scanner (high resolution PET brain imager)
3 whole body PET/CT scanners
2 multi node computer clusters

Current Research

Kinetic Modeling of Gd Transport through Kidneys

Improved Attenuation Correction in Myocardial PET/CT Imaging

Application of Diffusion Tensor MRI to Study Neurologic Disease

Motion Correction in Neuro PET Imaging

Nonparametric Estimation of Fluid Velocity from Phase-Contrast MRI

Amino Acid Transport into Tumors as a Function of Tumor Grade

Comparision of Beta Amyloid Deposits in the Brains of Patients with Late Life Depression and  Alzheimer’s Disease

Quantitative Myocardial Blood Flow Measurements

SERT Modeling in Depression

Therapeutic Drug Occupancy Studies.

Faculty

John Votaw, PhD
Jon Nye, PHD
John Carew, PhD

Research Associates

Jacob David - Lab Manager
Nivedata Raghunath, MS
Dana Tudorascu

Contact Information

Mary David
E-mail: mary.david@emoryhealthcare.org

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